Latent TGF-β1 protects against diabetic kidney disease via Arkadia/Smad7 signaling

TGF-β1 has long been considered as a key mediator in diabetic kidney disease (DKD) but anti-TGF-β1 treatment fails clinically, suggesting a diverse role for TGF-β1 in DKD. In the present study, we examined a novel hypothesis that latent TGF-β1 may be protective in DKD mice overexpressing human laten...

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Detalles Bibliográficos
Autores principales: Wu, Weifeng, Huang, Xiao R., You, Yongke, Xue, Liang, Wang, Xiao-Jing, Meng, Xiaoming, Lin, Xiang, Shen, Jiangang, Yu, Xueqing, Lan, Hui-Yao, Chen, Haiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416717/
https://www.ncbi.nlm.nih.gov/pubmed/34512167
http://dx.doi.org/10.7150/ijbs.61647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416717/
https://www.ncbi.nlm.nih.gov/pubmed/34512167
http://dx.doi.org/10.7150/ijbs.61647

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