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CD47/SIRPα pathway mediates cancer immune escape and immunotherapy

The adaptive immune checkpoints such as PD-1(programmed death-1)/PD-L1 (programmed death-ligand 1) play an important role in cancer immunotherapy, whereas increasing evidence suggests that cancer cell evades immune surveillance by innate immune checkpoints such as SIRPα (signal-regulatory protein α)...

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Detalles Bibliográficos
Autores principales: Jia, Xiao, Yan, Bingjun, Tian, Xiaoqing, Liu, Qian, Jin, Jianhua, Shi, Juanjuan, Hou, Yongzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416724/
https://www.ncbi.nlm.nih.gov/pubmed/34512146
http://dx.doi.org/10.7150/ijbs.60782