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CCNB2/SASP/Cathepsin B & PGE2 Axis Induce Cell Senescence Mediated Malignant Transformation

Glioma is the most frequent and aggressive adult brain tumor with maximum mortality. However, the gene alteration and mechanism underlying malignant transformation of glioma remain largely unknown. We aimed to find key factors regulating tumor progression and malignant transformation of glioma. Here...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Zhang, Hanbing, Wang, Minglei, He, Jing, Guo, Hui, Li, Lihua, Wang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416730/
https://www.ncbi.nlm.nih.gov/pubmed/34512164
http://dx.doi.org/10.7150/ijbs.63430