miR-139/PDE2A-Notch1 feedback circuit represses stemness of gliomas by inhibiting Wnt/β-catenin signaling

Rationale: The malignant phenotypes of glioblastomas (GBMs) are primarily attributed to glioma stem cells (GSCs). Our previous study and other reports have suggested that both miR-139 and its host gene PDE2A are putative antitumor genes in various cancers. The aim of this study was to investigate th...

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Detalles Bibliográficos
Autores principales: Li, San-Zhong, Ren, Kai-Xi, Zhao, Jing, Wu, Shuang, Li, Juan, Zang, Jian, Fei, Zhou, Zhao, Jun-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416740/
https://www.ncbi.nlm.nih.gov/pubmed/34512162
http://dx.doi.org/10.7150/ijbs.62858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416740/
https://www.ncbi.nlm.nih.gov/pubmed/34512162
http://dx.doi.org/10.7150/ijbs.62858

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