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Dynamic Modeling of Mitochondrial Membrane Potential Upon Exposure to Mitochondrial Inhibitors
Mitochondria are the main bioenergetic organelles of cells. Exposure to chemicals targeting mitochondria therefore generally results in the development of toxicity. The cellular response to perturbations in cellular energy production is a balance between adaptation, by reorganisation and organelle b...
Autores principales: | Yang, Huan, van der Stel, Wanda, Lee, Randy, Bauch, Caroline, Bevan, Sam, Walker, Paul, van de Water, Bob, Danen, Erik H. J., Beltman, Joost B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416757/ https://www.ncbi.nlm.nih.gov/pubmed/34489692 http://dx.doi.org/10.3389/fphar.2021.679407 |
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