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The yoga of Rag GTPases: Dynamic structural poses confer amino acid sensing by mTORC1
Heterodimeric Rag GTPases play a critical role in relaying fluctuating levels of cellular amino acids to the sensor mechanistic target of rapamycin complex 1. Important mechanistic questions remain unresolved, however, regarding how guanine nucleotide binding enables Rag GTPases to transition dynami...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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American Society for Biochemistry and Molecular Biology
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416955/ https://www.ncbi.nlm.nih.gov/pubmed/34419448 http://dx.doi.org/10.1016/j.jbc.2021.101103 |