Overcoming the compensatory elevation of NRF2 renders hepatocellular carcinoma cells more vulnerable to disulfiram/copper-induced ferroptosis

Hepatocellular carcinoma (HCC) is one of the paramount causes of cancer-related death worldwide. Despite recent advances have been made in clinical treatments of HCC, the general prognosis of patients remains poor. Therefore, it is imperative to develop a less toxic and more effective therapeutic st...

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Detalles Bibliográficos
Autores principales: Ren, Xueying, Li, Yanchun, Zhou, Yi, Hu, Wanye, Yang, Chen, Jing, Qiangan, Zhou, Chaoting, Wang, Xu, Hu, Jiayu, Wang, Luyang, Yang, Jing, Wang, Hairui, Xu, Haifeng, Li, Huanjuan, Tong, Xiangmin, Wang, Ying, Du, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416961/
https://www.ncbi.nlm.nih.gov/pubmed/34482117
http://dx.doi.org/10.1016/j.redox.2021.102122

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