METTL3-mediated m(6)A mRNA modification promotes esophageal cancer initiation and progression via Notch signaling pathway

Esophageal cancer is a lethal malignancy with a high mortality rate, while the molecular mechanisms underlying esophageal cancer pathogenesis are still poorly understood. Here, we found that the N6-methyladenosine (m(6)A) methyltransferase-like 3 (METTL3) is significantly upregulated in esophageal s...

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Detalles Bibliográficos
Autores principales: Han, Hui, Yang, Chunlong, Zhang, Shuishen, Cheng, Maosheng, Guo, Siyao, Zhu, Yan, Ma, Jieyi, Liang, Yu, Wang, Lu, Zheng, Siyi, Wang, Zhaoyu, Chen, Demeng, Jiang, Yi-Zhou, Lin, Shuibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8416973/
https://www.ncbi.nlm.nih.gov/pubmed/34513313
http://dx.doi.org/10.1016/j.omtn.2021.07.007

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