Cargando…

miR-98-5p plays a critical role in depression and antidepressant effect of ketamine

Ketamine has been demonstrated to be a rapid-onset and long-lasting antidepressant, but its underlying molecular mechanisms remain unclear. Recent studies have emerged microRNAs as important modulators for depression treatment. In this study, we report that miR-98-5p is downregulated in the prefront...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Chaoli, Wang, Yuanyuan, Wu, Zifeng, Xu, Jiali, Zhou, Ling, Wang, Di, Yang, Ling, Zhu, Bin, Chen, Guiquan, Liu, Cunming, Yang, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417029/ https://www.ncbi.nlm.nih.gov/pubmed/34480014 http://dx.doi.org/10.1038/s41398-021-01588-0

Ejemplares similares

Prefrontal cortex miR-29b-3p plays a key role in the antidepressant-like effect of ketamine in rats
por: Wan, Yun-Qiang, et al.
Publicado: (2018)

Association of plasma VEGF levels and the antidepressant effects of ketamine in patients with depression
por: Zheng, Wei, et al.
Publicado: (2021)

Correction: Prefrontal cortex miR-29b-3p plays a key role in the antidepressant-like effect of ketamine in rats
por: Wan, Yun-Qiang, et al.
Publicado: (2022)

Pre-treatment Pain Symptoms Influence Antidepressant Response to Ketamine in Depressive Patients
por: Lan, Xiaofeng, et al.
Publicado: (2022)

Rapid Antidepressant Response with Ketamine: Is it the Solution to Resistant Depression?
por: Thakurta, Rajarshi Guha, et al.
Publicado: (2012)

Plasma BDNF concentrations and the antidepressant effects of six ketamine infusions in unipolar and bipolar depression
por: Zheng, Wei, et al.
Publicado: (2021)

Immunoregulation and antidepressant effect of ketamine
por: Zhang, Nan, et al.
Publicado: (2021)

Functional connectivity of the amygdala and the antidepressant and antisuicidal effects of repeated ketamine infusions in major depressive disorder
por: Liu, Haiyan, et al.
Publicado: (2023)

GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine
por: Miller, Oliver H, et al.
Publicado: (2014)

Th17 Cells in Depression: Are They Crucial for the Antidepressant Effect of Ketamine?
por: Cui, Meiying, et al.
Publicado: (2021)

Neurocognitive effects of six ketamine infusions and the association with antidepressant effects in treatment-resistant bipolar depression: a preliminary study
por: Zheng, Wei, et al.
Publicado: (2020)

The soluble epoxide hydrolase inhibitor TPPU improves comorbidity of chronic pain and depression via the AHR and TSPO signaling
por: Luo, Ailin, et al.
Publicado: (2023)

Ketamine: stimulating antidepressant treatment?
por: Malhi, Gin S., et al.
Publicado: (2016)

Comparison of R-ketamine and rapastinel antidepressant effects in the social defeat stress model of depression
por: Yang, Bangkun, et al.
Publicado: (2016)

Targeting inflammation in depression: Ketamine as an anti-inflammatory antidepressant in psychiatric emergency
por: Nikkheslat, Naghmeh
Publicado: (2021)

Uncovering the Underlying Mechanisms of Ketamine as a Novel Antidepressant
por: Xu, Songbai, et al.
Publicado: (2022)

Role of depressive symptoms in the prognosis of heart failure and its potential clinical predictors
por: Duan, Jiahao, et al.
Publicado: (2022)

The Role of the Gastrointestinal System in Neuroinvasion by SARS-CoV-2
por: Xu, Jiali, et al.
Publicado: (2021)

Investigation of miR-1202, miR-135a, and miR-16 in Major Depressive Disorder and Antidepressant Response
por: Fiori, Laura M, et al.
Publicado: (2017)

Sirtuin 3 Plays a Critical Role in the Antidepressant- and Anxiolytic-like Effects of Kaempferol
por: Li, Hao-Yuan, et al.
Publicado: (2022)

The Ketamine Antidepressant Story: New Insights
por: Alshammari, Tahani K.
Publicado: (2020)

The role of dissociation in ketamine’s antidepressant effects
por: Ballard, Elizabeth D., et al.
Publicado: (2020)

The antidepressant properties of ketamine (literature review)
por: Chamsi, F. Z., et al.
Publicado: (2023)

A Bibliometric Analysis of Research on the Role of BDNF in Depression and Treatment
por: He, Teng, et al.
Publicado: (2022)

Antidepressant effects of ketamine: mechanisms underlying fast-acting novel antidepressants
por: Browne, Caroline A., et al.
Publicado: (2013)

Aberrant Expression of Intracellular let-7e, miR-146a, and miR-155 Correlates with Severity of Depression in Patients with Major Depressive Disorder and Is Ameliorated after Antidepressant Treatment
por: Hung, Yi-Yung, et al.
Publicado: (2019)

Deleterious effects of nervous system in the offspring following maternal SARS-CoV-2 infection during the COVID-19 pandemic
por: Wang, Ruting, et al.
Publicado: (2022)

Sustained antidepressant effect of ketamine through NMDAR trapping in the LHb
por: Ma, Shuangshuang, et al.
Publicado: (2023)

High glucose concentration induces endothelial cell proliferation by regulating cyclin‐D2‐related miR‐98
por: Li, Xin‐Xin, et al.
Publicado: (2016)

Ketamine and rapid-acting antidepressants: a new era in the battle against depression and suicide
por: Duman, Ronald S.
Publicado: (2018)

Ketamine as Antidepressant? Current State and Future Perspectives
por: Hasselmann, H. W.W.
Publicado: (2014)

Is Metabolism of (R)-Ketamine Essential for the Antidepressant Effects?
por: Chaki, Shigeyuki
Publicado: (2017)

Structural Integrity in the Sustained Antidepressant Effect of Ketamine
por: Belujon, Pauline
Publicado: (2017)

Ketamine: a new chapter in antidepressant development
por: Zarate, Carlos A.
Publicado: (2020)

Aspirin ameliorates lung cancer by targeting the miR‐98/WNT1 axis
por: Gan, Huizhu, et al.
Publicado: (2019)

Exosomal let-7e, miR-21-5p, miR-145, miR-146a and miR-155 in Predicting Antidepressants Response in Patients with Major Depressive Disorder
por: Hung, Yi-Yung, et al.
Publicado: (2021)

MiR-155 is involved in major depression disorder and antidepressant treatment via targeting SIRT1
por: Wang, Xun, et al.
Publicado: (2018)

Activation of σ1-Receptors by R-Ketamine May Enhance the Antidepressant Effect of S-Ketamine
por: Kalkman, Hans O.
Publicado: (2023)

Hydroxynorketamine: Implications for the NMDA Receptor Hypothesis of Ketamine’s Antidepressant Action
por: Aleksandrova, Lily R., et al.
Publicado: (2017)

miR-1202: A Primate Specific and Brain Enriched miRNA Involved in Major Depression and Antidepressant Treatment
por: Lopez, Juan Pablo, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_r5g54c0kup7djf9rgmnfa37m0l