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A Methodological Approach Using rAAV Vectors Encoding Nanobody-Based Biologics to Evaluate ARTC2.2 and P2X7 In Vivo

On murine T cells, mono-ADP ribosyltransferase ARTC2.2 catalyzes ADP-ribosylation of various surface proteins when nicotinamide adenine dinucleotide (NAD(+)) is released into the extracellular compartment. Covalent ADP-ribosylation of the P2X7 receptor by ARTC2.2 thereby represents an additional mec...

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Detalles Bibliográficos
Autores principales:	Gondé, Henri, Demeules, Mélanie, Hardet, Romain, Scarpitta, Allan, Junge, Marten, Pinto-Espinoza, Carolina, Varin, Rémi, Koch-Nolte, Friedrich, Boyer, Olivier, Adriouch, Sahil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417108/ https://www.ncbi.nlm.nih.gov/pubmed/34489954 http://dx.doi.org/10.3389/fimmu.2021.704408

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