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Loss of PIKfyve Causes Transdifferentiation of Dictyostelium Spores Into Basal Disc Cells

The 1-phosphatidylinositol-3-phosphate 5-kinase PIKfyve generates PtdIns3,5P2 on late phagolysosomes, which by recruiting the scission protein Atg18, results in their fragmentation in the normal course of endosome processing. Loss of PIKfyve function causes cellular hypervacuolization in eukaryotes...

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Detalles Bibliográficos
Autores principales:	Yamada, Yoko, Forbes, Gillian, Du, Qingyou, Kawata, Takefumi, Schaap, Pauline
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417116/ https://www.ncbi.nlm.nih.gov/pubmed/34490246 http://dx.doi.org/10.3389/fcell.2021.692473

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