Matrilin3/TGFβ3 gelatin microparticles promote chondrogenesis, prevent hypertrophy, and induce paracrine release in MSC spheroid for disc regeneration

Degenerative disc disease (DDD) is the leading cause of excruciating lower back pain and disability in adults worldwide. Among the current treatments for DDD, cell-based therapies such as the injection of both disc- and non-disc-derived chondrocytes have shown significant improvements in the patient...

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Detalles Bibliográficos
Autores principales: Bello, Alvin Bacero, Kim, Yunkyung, Park, Sunghyun, Muttigi, Manjunatha S., Kim, Jiseong, Park, Hansoo, Lee, Soohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417285/
https://www.ncbi.nlm.nih.gov/pubmed/34480032
http://dx.doi.org/10.1038/s41536-021-00160-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417285/
https://www.ncbi.nlm.nih.gov/pubmed/34480032
http://dx.doi.org/10.1038/s41536-021-00160-0

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