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First-in-Human Evaluation of Positron Emission Tomography/Computed Tomography With [(18)F]FB(ePEG12)12-Exendin-4: A Phase 1 Clinical Study Targeting GLP-1 Receptor Expression Cells in Pancreas

Pancreatic β-cell mass (BCM) has a central importance in the pathophysiology of diabetes mellitus. Recently, pancreatic β-cell-specific imaging, especially positron emission tomography (PET) with exendin-based probes, has emerged for non-invasive evaluation of BCM. We developed a novel exendin-based...

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Detalles Bibliográficos
Autores principales:	Fujimoto, Hiroyuki, Fujita, Naotaka, Hamamatsu, Keita, Murakami, Takaaki, Nakamoto, Yuji, Saga, Tsuneo, Ishimori, Takayoshi, Shimizu, Yoichi, Watanabe, Hiroyuki, Sano, Kohei, Harada, Norio, Nakamura, Hiroshi, Toyoda, Kentaro, Kimura, Hiroyuki, Nakagawa, Shunsaku, Hirai, Mitsuharu, Murakami, Atsushi, Ono, Masahiro, Togashi, Kaori, Saji, Hideo, Inagaki, Nobuya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417326/ https://www.ncbi.nlm.nih.gov/pubmed/34489868 http://dx.doi.org/10.3389/fendo.2021.717101

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