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Vascular smooth muscle cell dysfunction contribute to neuroinflammation and Tau hyperphosphorylation in Alzheimer disease
Despite the emerging evidence implying early vascular contributions to neurodegenerative syndromes, the role of vascular smooth muscle cells (VSMCs) in the pathogenesis of Alzheimer disease (AD) is still not well understood. Herein, we show that VSMCs in brains of patients with AD and animal models...
Autores principales: | Aguilar-Pineda, Jorge A., Vera-Lopez, Karin J., Shrivastava, Pallavi, Chávez-Fumagalli, Miguel A., Nieto-Montesinos, Rita, Alvarez-Fernandez, Karla L., Goyzueta Mamani, Luis D., Davila Del-Carpio, Gonzalo, Gomez-Valdez, Badhin, Miller, Clint L., Malhotra, Rajeev, Lindsay, Mark E., Lino Cardenas, Christian L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417400/ https://www.ncbi.nlm.nih.gov/pubmed/34505007 http://dx.doi.org/10.1016/j.isci.2021.102993 |
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