Cargando…
The phosphatidylserine flippase β-subunit Tmem30a is essential for normal insulin maturation and secretion
The processing, maturation, and secretion of insulin are under precise regulation, and dysregulation causes profound defects in glucose handling, leading to diabetes. Tmem30a is the β subunit of the phosphatidylserine (PS) flippase, which maintains the membrane asymmetric distribution of PS. Tmem30a...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417432/ https://www.ncbi.nlm.nih.gov/pubmed/33895325 http://dx.doi.org/10.1016/j.ymthe.2021.04.026 |