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The phosphatidylserine flippase β-subunit Tmem30a is essential for normal insulin maturation and secretion

The processing, maturation, and secretion of insulin are under precise regulation, and dysregulation causes profound defects in glucose handling, leading to diabetes. Tmem30a is the β subunit of the phosphatidylserine (PS) flippase, which maintains the membrane asymmetric distribution of PS. Tmem30a...

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Detalles Bibliográficos
Autores principales:	Yang, Yeming, Sun, Kuanxiang, Liu, Wenjing, Li, Xiao, Tian, Wanli, Shuai, Ping, Zhu, Xianjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417432/ https://www.ncbi.nlm.nih.gov/pubmed/33895325 http://dx.doi.org/10.1016/j.ymthe.2021.04.026

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