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Increase in Blood–Brain Barrier Permeability is Modulated by Tissue Kallikrein via Activation of Bradykinin B1 and B2 Receptor-Mediated Signaling

AIM: Disruption of the blood–brain barrier (BBB) is a critical pathological feature after stroke. Although tissue kallikrein (TK) has used in the treatment of stroke in China, the role of TK in modulating BBB permeability is not clear. METHODS: We investigated the effect of different doses of TK on...

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Detalles Bibliográficos
Autores principales:	Zhang, Qin, Tan, Juan, Wan, Li, Chen, Chao, Wu, Bin, Ke, Xijian, Wu, Rongxue, Ran, Xiao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417820/ https://www.ncbi.nlm.nih.gov/pubmed/34511968 http://dx.doi.org/10.2147/JIR.S322225

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