Pharmacodynamics and Pharmacokinetics of Injectable Pimobendan and Its Metabolite, O-Desmethyl-Pimobendan, in Healthy Dogs

Objectives: This study was designed to thoroughly evaluate the effects of bolus pimobendan at a dose of 0.15 mg/kg on cardiac functions, hemodynamics, and electrocardiographic parameters together with the pharmacokinetic profile of pimobendan and its active metabolite, o-desmethyl-pimobendan (ODMP),...

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Detalles Bibliográficos
Autores principales: Pichayapaiboon, Poonavit, Tantisuwat, Lalida, Boonpala, Pakit, Saengklub, Nakkawee, Boonyarattanasoonthorn, Tussapon, Khemawoot, Phisit, Kijtawornrat, Anusak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Veterinary Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417876/
https://www.ncbi.nlm.nih.gov/pubmed/34490386
http://dx.doi.org/10.3389/fvets.2021.656902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417876/
https://www.ncbi.nlm.nih.gov/pubmed/34490386
http://dx.doi.org/10.3389/fvets.2021.656902

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