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Pharmacodynamics and Pharmacokinetics of Injectable Pimobendan and Its Metabolite, O-Desmethyl-Pimobendan, in Healthy Dogs

Objectives: This study was designed to thoroughly evaluate the effects of bolus pimobendan at a dose of 0.15 mg/kg on cardiac functions, hemodynamics, and electrocardiographic parameters together with the pharmacokinetic profile of pimobendan and its active metabolite, o-desmethyl-pimobendan (ODMP),...

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Detalles Bibliográficos
Autores principales:	Pichayapaiboon, Poonavit, Tantisuwat, Lalida, Boonpala, Pakit, Saengklub, Nakkawee, Boonyarattanasoonthorn, Tussapon, Khemawoot, Phisit, Kijtawornrat, Anusak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Veterinary Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417876/ https://www.ncbi.nlm.nih.gov/pubmed/34490386 http://dx.doi.org/10.3389/fvets.2021.656902

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