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Sclerosing Mesenteritis, a Rare Cause of Mesenteric Mass in a Young Adult: A Case Report

Sclerosing mesenteritis (SM) is a rare fibroinflammatory disorder that involves mesenteric adipose tissue, more frequently localized in the small intestine, with an insidious clinical presentation having symptoms related to mass effect, usually resulting in bowel obstruction, mesenteric ischemia, as...

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Autores principales: Piombino, Eliana, D'Agata, Costanza, Picardo, Maria Carolina, Caltavuturo, Claudia, Magro, Gaetano, Colarossi, Cristina, Memeo, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417936/
https://www.ncbi.nlm.nih.gov/pubmed/34490340
http://dx.doi.org/10.3389/fsurg.2021.722312
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author Piombino, Eliana
D'Agata, Costanza
Picardo, Maria Carolina
Caltavuturo, Claudia
Magro, Gaetano
Colarossi, Cristina
Memeo, Lorenzo
author_facet Piombino, Eliana
D'Agata, Costanza
Picardo, Maria Carolina
Caltavuturo, Claudia
Magro, Gaetano
Colarossi, Cristina
Memeo, Lorenzo
author_sort Piombino, Eliana
collection PubMed
description Sclerosing mesenteritis (SM) is a rare fibroinflammatory disorder that involves mesenteric adipose tissue, more frequently localized in the small intestine, with an insidious clinical presentation having symptoms related to mass effect, usually resulting in bowel obstruction, mesenteric ischemia, as well as rapid weight loss. We report a case of a 23-year-old male presenting with palpable abdominal mass, mesogastric pain, and a history of rapid weight loss, who underwent exploratory laparoscopy. A hemorrhagic and gelatinous nodular tumor mass of the mesentery was identified and the surgical procedure was converted to a laparotomic approach. Histologically, the mass was composed of a proliferation of bland-looking spindle cells with slightly eosinophilic cytoplasm and elongated normochromatic nuclei with mild nuclear atypia, haphazardly set in a collagenized stroma; fat necrosis and inflammatory cells (lymphocytes, plasma-cells, and histiocytes) were also evident. The diagnosis of sclerosing mesenteritis was made. Our case emphasizes that histology remains pre-eminent for a correct diagnosis of SM, as pre-operative radiological-based diagnosis is non-specific.
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spelling pubmed-84179362021-09-05 Sclerosing Mesenteritis, a Rare Cause of Mesenteric Mass in a Young Adult: A Case Report Piombino, Eliana D'Agata, Costanza Picardo, Maria Carolina Caltavuturo, Claudia Magro, Gaetano Colarossi, Cristina Memeo, Lorenzo Front Surg Surgery Sclerosing mesenteritis (SM) is a rare fibroinflammatory disorder that involves mesenteric adipose tissue, more frequently localized in the small intestine, with an insidious clinical presentation having symptoms related to mass effect, usually resulting in bowel obstruction, mesenteric ischemia, as well as rapid weight loss. We report a case of a 23-year-old male presenting with palpable abdominal mass, mesogastric pain, and a history of rapid weight loss, who underwent exploratory laparoscopy. A hemorrhagic and gelatinous nodular tumor mass of the mesentery was identified and the surgical procedure was converted to a laparotomic approach. Histologically, the mass was composed of a proliferation of bland-looking spindle cells with slightly eosinophilic cytoplasm and elongated normochromatic nuclei with mild nuclear atypia, haphazardly set in a collagenized stroma; fat necrosis and inflammatory cells (lymphocytes, plasma-cells, and histiocytes) were also evident. The diagnosis of sclerosing mesenteritis was made. Our case emphasizes that histology remains pre-eminent for a correct diagnosis of SM, as pre-operative radiological-based diagnosis is non-specific. Frontiers Media S.A. 2021-08-20 /pmc/articles/PMC8417936/ /pubmed/34490340 http://dx.doi.org/10.3389/fsurg.2021.722312 Text en Copyright © 2021 Piombino, D'Agata, Picardo, Caltavuturo, Magro, Colarossi and Memeo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Piombino, Eliana
D'Agata, Costanza
Picardo, Maria Carolina
Caltavuturo, Claudia
Magro, Gaetano
Colarossi, Cristina
Memeo, Lorenzo
Sclerosing Mesenteritis, a Rare Cause of Mesenteric Mass in a Young Adult: A Case Report
title Sclerosing Mesenteritis, a Rare Cause of Mesenteric Mass in a Young Adult: A Case Report
title_full Sclerosing Mesenteritis, a Rare Cause of Mesenteric Mass in a Young Adult: A Case Report
title_fullStr Sclerosing Mesenteritis, a Rare Cause of Mesenteric Mass in a Young Adult: A Case Report
title_full_unstemmed Sclerosing Mesenteritis, a Rare Cause of Mesenteric Mass in a Young Adult: A Case Report
title_short Sclerosing Mesenteritis, a Rare Cause of Mesenteric Mass in a Young Adult: A Case Report
title_sort sclerosing mesenteritis, a rare cause of mesenteric mass in a young adult: a case report
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417936/
https://www.ncbi.nlm.nih.gov/pubmed/34490340
http://dx.doi.org/10.3389/fsurg.2021.722312
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