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Sclerosing Mesenteritis, a Rare Cause of Mesenteric Mass in a Young Adult: A Case Report
Sclerosing mesenteritis (SM) is a rare fibroinflammatory disorder that involves mesenteric adipose tissue, more frequently localized in the small intestine, with an insidious clinical presentation having symptoms related to mass effect, usually resulting in bowel obstruction, mesenteric ischemia, as...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417936/ https://www.ncbi.nlm.nih.gov/pubmed/34490340 http://dx.doi.org/10.3389/fsurg.2021.722312 |
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author | Piombino, Eliana D'Agata, Costanza Picardo, Maria Carolina Caltavuturo, Claudia Magro, Gaetano Colarossi, Cristina Memeo, Lorenzo |
author_facet | Piombino, Eliana D'Agata, Costanza Picardo, Maria Carolina Caltavuturo, Claudia Magro, Gaetano Colarossi, Cristina Memeo, Lorenzo |
author_sort | Piombino, Eliana |
collection | PubMed |
description | Sclerosing mesenteritis (SM) is a rare fibroinflammatory disorder that involves mesenteric adipose tissue, more frequently localized in the small intestine, with an insidious clinical presentation having symptoms related to mass effect, usually resulting in bowel obstruction, mesenteric ischemia, as well as rapid weight loss. We report a case of a 23-year-old male presenting with palpable abdominal mass, mesogastric pain, and a history of rapid weight loss, who underwent exploratory laparoscopy. A hemorrhagic and gelatinous nodular tumor mass of the mesentery was identified and the surgical procedure was converted to a laparotomic approach. Histologically, the mass was composed of a proliferation of bland-looking spindle cells with slightly eosinophilic cytoplasm and elongated normochromatic nuclei with mild nuclear atypia, haphazardly set in a collagenized stroma; fat necrosis and inflammatory cells (lymphocytes, plasma-cells, and histiocytes) were also evident. The diagnosis of sclerosing mesenteritis was made. Our case emphasizes that histology remains pre-eminent for a correct diagnosis of SM, as pre-operative radiological-based diagnosis is non-specific. |
format | Online Article Text |
id | pubmed-8417936 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-84179362021-09-05 Sclerosing Mesenteritis, a Rare Cause of Mesenteric Mass in a Young Adult: A Case Report Piombino, Eliana D'Agata, Costanza Picardo, Maria Carolina Caltavuturo, Claudia Magro, Gaetano Colarossi, Cristina Memeo, Lorenzo Front Surg Surgery Sclerosing mesenteritis (SM) is a rare fibroinflammatory disorder that involves mesenteric adipose tissue, more frequently localized in the small intestine, with an insidious clinical presentation having symptoms related to mass effect, usually resulting in bowel obstruction, mesenteric ischemia, as well as rapid weight loss. We report a case of a 23-year-old male presenting with palpable abdominal mass, mesogastric pain, and a history of rapid weight loss, who underwent exploratory laparoscopy. A hemorrhagic and gelatinous nodular tumor mass of the mesentery was identified and the surgical procedure was converted to a laparotomic approach. Histologically, the mass was composed of a proliferation of bland-looking spindle cells with slightly eosinophilic cytoplasm and elongated normochromatic nuclei with mild nuclear atypia, haphazardly set in a collagenized stroma; fat necrosis and inflammatory cells (lymphocytes, plasma-cells, and histiocytes) were also evident. The diagnosis of sclerosing mesenteritis was made. Our case emphasizes that histology remains pre-eminent for a correct diagnosis of SM, as pre-operative radiological-based diagnosis is non-specific. Frontiers Media S.A. 2021-08-20 /pmc/articles/PMC8417936/ /pubmed/34490340 http://dx.doi.org/10.3389/fsurg.2021.722312 Text en Copyright © 2021 Piombino, D'Agata, Picardo, Caltavuturo, Magro, Colarossi and Memeo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Surgery Piombino, Eliana D'Agata, Costanza Picardo, Maria Carolina Caltavuturo, Claudia Magro, Gaetano Colarossi, Cristina Memeo, Lorenzo Sclerosing Mesenteritis, a Rare Cause of Mesenteric Mass in a Young Adult: A Case Report |
title | Sclerosing Mesenteritis, a Rare Cause of Mesenteric Mass in a Young Adult: A Case Report |
title_full | Sclerosing Mesenteritis, a Rare Cause of Mesenteric Mass in a Young Adult: A Case Report |
title_fullStr | Sclerosing Mesenteritis, a Rare Cause of Mesenteric Mass in a Young Adult: A Case Report |
title_full_unstemmed | Sclerosing Mesenteritis, a Rare Cause of Mesenteric Mass in a Young Adult: A Case Report |
title_short | Sclerosing Mesenteritis, a Rare Cause of Mesenteric Mass in a Young Adult: A Case Report |
title_sort | sclerosing mesenteritis, a rare cause of mesenteric mass in a young adult: a case report |
topic | Surgery |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417936/ https://www.ncbi.nlm.nih.gov/pubmed/34490340 http://dx.doi.org/10.3389/fsurg.2021.722312 |
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