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NEDD8 Deamidation Inhibits Cullin RING Ligase Dynamics

Cullin-RING ligases (CRLs) are a significant subset of Ubiquitin E3 ligases that regulate multiple cellular substrates involved in innate immunity, cytoskeleton modeling, and cell cycle. The glutamine deamidase Cycle inhibitory factor (Cif) from enteric bacteria inactivates CRLs to modulate these pr...

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Detalles Bibliográficos
Autores principales: Mohanty, Priyesh, Chatterjee, Kiran Sankar, Das, Ranabir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418054/
https://www.ncbi.nlm.nih.gov/pubmed/34489942
http://dx.doi.org/10.3389/fimmu.2021.695331