Cargando…

Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas)

Myeloid sarcoma is a rare ocular manifestation of acute myeloid leukemia. Bilateral manifestation preceding any clinical signs of leukemia is even rarer. We here report the case of a 16-month-old patient with rapidly progressive, inflammatory, acute bilateral exophthalmos associated with exposure ke...

Descripción completa

Detalles Bibliográficos
Autores principales: Rambeloson, Rado, Ranoasy, Njara Francia, Randrianjafisamindrakotroka, Ony, Andriamiadanalisoa, Andoniaina Orlando, Raobela, Léa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418160/
https://www.ncbi.nlm.nih.gov/pubmed/34527161
http://dx.doi.org/10.11604/pamj.2021.39.145.25242
Descripción
Sumario:Myeloid sarcoma is a rare ocular manifestation of acute myeloid leukemia. Bilateral manifestation preceding any clinical signs of leukemia is even rarer. We here report the case of a 16-month-old patient with rapidly progressive, inflammatory, acute bilateral exophthalmos associated with exposure keratitis. Computed tomography (CT) scan of the orbit and of the brain showed bilateral tissue-like infiltration into the orbital cavity. Blood tests showed biologic inflammatory syndrome, bicytopenia and circulating blasts 83%. Myelogram was performed based on the presence of circulating blasts; it showed acute myeloid leukemia (grade 4). Clinicians should suspect myeloid sarcoma in patients with bilateral exophthalmos and conduct a careful interpretation of blood test results.