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Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas)
Myeloid sarcoma is a rare ocular manifestation of acute myeloid leukemia. Bilateral manifestation preceding any clinical signs of leukemia is even rarer. We here report the case of a 16-month-old patient with rapidly progressive, inflammatory, acute bilateral exophthalmos associated with exposure ke...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418160/ https://www.ncbi.nlm.nih.gov/pubmed/34527161 http://dx.doi.org/10.11604/pamj.2021.39.145.25242 |
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author | Rambeloson, Rado Ranoasy, Njara Francia Randrianjafisamindrakotroka, Ony Andriamiadanalisoa, Andoniaina Orlando Raobela, Léa |
author_facet | Rambeloson, Rado Ranoasy, Njara Francia Randrianjafisamindrakotroka, Ony Andriamiadanalisoa, Andoniaina Orlando Raobela, Léa |
author_sort | Rambeloson, Rado |
collection | PubMed |
description | Myeloid sarcoma is a rare ocular manifestation of acute myeloid leukemia. Bilateral manifestation preceding any clinical signs of leukemia is even rarer. We here report the case of a 16-month-old patient with rapidly progressive, inflammatory, acute bilateral exophthalmos associated with exposure keratitis. Computed tomography (CT) scan of the orbit and of the brain showed bilateral tissue-like infiltration into the orbital cavity. Blood tests showed biologic inflammatory syndrome, bicytopenia and circulating blasts 83%. Myelogram was performed based on the presence of circulating blasts; it showed acute myeloid leukemia (grade 4). Clinicians should suspect myeloid sarcoma in patients with bilateral exophthalmos and conduct a careful interpretation of blood test results. |
format | Online Article Text |
id | pubmed-8418160 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-84181602021-09-14 Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas) Rambeloson, Rado Ranoasy, Njara Francia Randrianjafisamindrakotroka, Ony Andriamiadanalisoa, Andoniaina Orlando Raobela, Léa Pan Afr Med J Case Report Myeloid sarcoma is a rare ocular manifestation of acute myeloid leukemia. Bilateral manifestation preceding any clinical signs of leukemia is even rarer. We here report the case of a 16-month-old patient with rapidly progressive, inflammatory, acute bilateral exophthalmos associated with exposure keratitis. Computed tomography (CT) scan of the orbit and of the brain showed bilateral tissue-like infiltration into the orbital cavity. Blood tests showed biologic inflammatory syndrome, bicytopenia and circulating blasts 83%. Myelogram was performed based on the presence of circulating blasts; it showed acute myeloid leukemia (grade 4). Clinicians should suspect myeloid sarcoma in patients with bilateral exophthalmos and conduct a careful interpretation of blood test results. The African Field Epidemiology Network 2021-06-23 /pmc/articles/PMC8418160/ /pubmed/34527161 http://dx.doi.org/10.11604/pamj.2021.39.145.25242 Text en Copyright: Rado Rambeloson et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Rambeloson, Rado Ranoasy, Njara Francia Randrianjafisamindrakotroka, Ony Andriamiadanalisoa, Andoniaina Orlando Raobela, Léa Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas) |
title | Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas) |
title_full | Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas) |
title_fullStr | Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas) |
title_full_unstemmed | Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas) |
title_short | Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas) |
title_sort | sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas) |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418160/ https://www.ncbi.nlm.nih.gov/pubmed/34527161 http://dx.doi.org/10.11604/pamj.2021.39.145.25242 |
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