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Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas)

Myeloid sarcoma is a rare ocular manifestation of acute myeloid leukemia. Bilateral manifestation preceding any clinical signs of leukemia is even rarer. We here report the case of a 16-month-old patient with rapidly progressive, inflammatory, acute bilateral exophthalmos associated with exposure ke...

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Autores principales: Rambeloson, Rado, Ranoasy, Njara Francia, Randrianjafisamindrakotroka, Ony, Andriamiadanalisoa, Andoniaina Orlando, Raobela, Léa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418160/
https://www.ncbi.nlm.nih.gov/pubmed/34527161
http://dx.doi.org/10.11604/pamj.2021.39.145.25242
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author Rambeloson, Rado
Ranoasy, Njara Francia
Randrianjafisamindrakotroka, Ony
Andriamiadanalisoa, Andoniaina Orlando
Raobela, Léa
author_facet Rambeloson, Rado
Ranoasy, Njara Francia
Randrianjafisamindrakotroka, Ony
Andriamiadanalisoa, Andoniaina Orlando
Raobela, Léa
author_sort Rambeloson, Rado
collection PubMed
description Myeloid sarcoma is a rare ocular manifestation of acute myeloid leukemia. Bilateral manifestation preceding any clinical signs of leukemia is even rarer. We here report the case of a 16-month-old patient with rapidly progressive, inflammatory, acute bilateral exophthalmos associated with exposure keratitis. Computed tomography (CT) scan of the orbit and of the brain showed bilateral tissue-like infiltration into the orbital cavity. Blood tests showed biologic inflammatory syndrome, bicytopenia and circulating blasts 83%. Myelogram was performed based on the presence of circulating blasts; it showed acute myeloid leukemia (grade 4). Clinicians should suspect myeloid sarcoma in patients with bilateral exophthalmos and conduct a careful interpretation of blood test results.
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spelling pubmed-84181602021-09-14 Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas) Rambeloson, Rado Ranoasy, Njara Francia Randrianjafisamindrakotroka, Ony Andriamiadanalisoa, Andoniaina Orlando Raobela, Léa Pan Afr Med J Case Report Myeloid sarcoma is a rare ocular manifestation of acute myeloid leukemia. Bilateral manifestation preceding any clinical signs of leukemia is even rarer. We here report the case of a 16-month-old patient with rapidly progressive, inflammatory, acute bilateral exophthalmos associated with exposure keratitis. Computed tomography (CT) scan of the orbit and of the brain showed bilateral tissue-like infiltration into the orbital cavity. Blood tests showed biologic inflammatory syndrome, bicytopenia and circulating blasts 83%. Myelogram was performed based on the presence of circulating blasts; it showed acute myeloid leukemia (grade 4). Clinicians should suspect myeloid sarcoma in patients with bilateral exophthalmos and conduct a careful interpretation of blood test results. The African Field Epidemiology Network 2021-06-23 /pmc/articles/PMC8418160/ /pubmed/34527161 http://dx.doi.org/10.11604/pamj.2021.39.145.25242 Text en Copyright: Rado Rambeloson et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Rambeloson, Rado
Ranoasy, Njara Francia
Randrianjafisamindrakotroka, Ony
Andriamiadanalisoa, Andoniaina Orlando
Raobela, Léa
Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas)
title Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas)
title_full Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas)
title_fullStr Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas)
title_full_unstemmed Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas)
title_short Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas)
title_sort sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas)
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418160/
https://www.ncbi.nlm.nih.gov/pubmed/34527161
http://dx.doi.org/10.11604/pamj.2021.39.145.25242
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