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A Rare Case of Tuberculosis as a Cause of Lytic Lesion of Talus Without Adjacent Bone Involvement in a Four-Year-Old Child

Extra-pulmonary tuberculosis still remains an important differential diagnosis for chronic musculoskeletal ailments in developing countries like India and may involve any part of the body without characteristic systemic features. We are presenting a rare case of a four-year-old female child, who cam...

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Autores principales: Sahoo, Samrat S, Tiwari, Vivek, Velagada, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418272/
https://www.ncbi.nlm.nih.gov/pubmed/34513482
http://dx.doi.org/10.7759/cureus.16909
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author Sahoo, Samrat S
Tiwari, Vivek
Velagada, Sandeep
author_facet Sahoo, Samrat S
Tiwari, Vivek
Velagada, Sandeep
author_sort Sahoo, Samrat S
collection PubMed
description Extra-pulmonary tuberculosis still remains an important differential diagnosis for chronic musculoskeletal ailments in developing countries like India and may involve any part of the body without characteristic systemic features. We are presenting a rare case of a four-year-old female child, who came to our tertiary-care hospital with chief complaints of pain in the left foot along with a gradually increasing swelling over the dorsum of the foot for the past five months. There was no history of trauma or constitutional symptoms. The serum inflammatory markers were found raised, and X-ray and magnetic resonance imaging revealed an isolated lytic lesion in the talus bone. Debridement, as well as curettage of the lesion, was done, both as a diagnostic and therapeutic procedure. A caseous cheesy material was evacuated and sent for microbiological and histopathological evaluation, which revealed the presence of acid-fast bacilli and granulomatous lesion confirming the diagnosis of tuberculosis. The patient was started with anti-tubercular chemotherapy, which continued for a total duration of 14 months, along with foot and ankle immobilization in a below-knee cast for three months. After completion of therapy, there was complete resolution of the lytic lesion on x-ray, with full symptom relief, and a full range of movement of the ankle was obtained. In cases with longstanding pain and swelling of the foot, with or without associated systemic symptoms, tuberculosis should be considered as a strong differential diagnosis even in young children, especially in developing countries. Diagnostic and therapeutic curettage along with anti-tubercular chemotherapy can result in a good functional outcome in such patients.
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spelling pubmed-84182722021-09-10 A Rare Case of Tuberculosis as a Cause of Lytic Lesion of Talus Without Adjacent Bone Involvement in a Four-Year-Old Child Sahoo, Samrat S Tiwari, Vivek Velagada, Sandeep Cureus Infectious Disease Extra-pulmonary tuberculosis still remains an important differential diagnosis for chronic musculoskeletal ailments in developing countries like India and may involve any part of the body without characteristic systemic features. We are presenting a rare case of a four-year-old female child, who came to our tertiary-care hospital with chief complaints of pain in the left foot along with a gradually increasing swelling over the dorsum of the foot for the past five months. There was no history of trauma or constitutional symptoms. The serum inflammatory markers were found raised, and X-ray and magnetic resonance imaging revealed an isolated lytic lesion in the talus bone. Debridement, as well as curettage of the lesion, was done, both as a diagnostic and therapeutic procedure. A caseous cheesy material was evacuated and sent for microbiological and histopathological evaluation, which revealed the presence of acid-fast bacilli and granulomatous lesion confirming the diagnosis of tuberculosis. The patient was started with anti-tubercular chemotherapy, which continued for a total duration of 14 months, along with foot and ankle immobilization in a below-knee cast for three months. After completion of therapy, there was complete resolution of the lytic lesion on x-ray, with full symptom relief, and a full range of movement of the ankle was obtained. In cases with longstanding pain and swelling of the foot, with or without associated systemic symptoms, tuberculosis should be considered as a strong differential diagnosis even in young children, especially in developing countries. Diagnostic and therapeutic curettage along with anti-tubercular chemotherapy can result in a good functional outcome in such patients. Cureus 2021-08-05 /pmc/articles/PMC8418272/ /pubmed/34513482 http://dx.doi.org/10.7759/cureus.16909 Text en Copyright © 2021, Sahoo et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Infectious Disease
Sahoo, Samrat S
Tiwari, Vivek
Velagada, Sandeep
A Rare Case of Tuberculosis as a Cause of Lytic Lesion of Talus Without Adjacent Bone Involvement in a Four-Year-Old Child
title A Rare Case of Tuberculosis as a Cause of Lytic Lesion of Talus Without Adjacent Bone Involvement in a Four-Year-Old Child
title_full A Rare Case of Tuberculosis as a Cause of Lytic Lesion of Talus Without Adjacent Bone Involvement in a Four-Year-Old Child
title_fullStr A Rare Case of Tuberculosis as a Cause of Lytic Lesion of Talus Without Adjacent Bone Involvement in a Four-Year-Old Child
title_full_unstemmed A Rare Case of Tuberculosis as a Cause of Lytic Lesion of Talus Without Adjacent Bone Involvement in a Four-Year-Old Child
title_short A Rare Case of Tuberculosis as a Cause of Lytic Lesion of Talus Without Adjacent Bone Involvement in a Four-Year-Old Child
title_sort rare case of tuberculosis as a cause of lytic lesion of talus without adjacent bone involvement in a four-year-old child
topic Infectious Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418272/
https://www.ncbi.nlm.nih.gov/pubmed/34513482
http://dx.doi.org/10.7759/cureus.16909
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