Cargando…

A rare case of pulmonary nocardiosis comorbid with Sjogren’s syndrome

BACKGROUND: Nocardia is an opportunistic pathogen, which occurs in patients with autoimmune diseases and immune dysfunction, and can cause bacteremia and other life‐threatening complications. The clinical manifestations of Nocardia pneumonia are similar to tuberculous and other clinical common bacte...

Descripción completa

Detalles Bibliográficos
Autores principales: Peng, Yumeng, Dong, Xiaoyan, Zhu, Yongze, Lv, Huoyang, Ge, Yumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418472/
https://www.ncbi.nlm.nih.gov/pubmed/34418167
http://dx.doi.org/10.1002/jcla.23902
_version_ 1783748576400113664
author Peng, Yumeng
Dong, Xiaoyan
Zhu, Yongze
Lv, Huoyang
Ge, Yumei
author_facet Peng, Yumeng
Dong, Xiaoyan
Zhu, Yongze
Lv, Huoyang
Ge, Yumei
author_sort Peng, Yumeng
collection PubMed
description BACKGROUND: Nocardia is an opportunistic pathogen, which occurs in patients with autoimmune diseases and immune dysfunction, and can cause bacteremia and other life‐threatening complications. The clinical manifestations of Nocardia pneumonia are similar to tuberculous and other clinical common bacterial pneumonia, but its antibacterial treatments are different and detection methods are unique, which may lead patients to suffer for many years due to clinical misdiagnosis and missed diagnosis. METHODS: Imaging and laboratory examinations were performed for preliminary diagnosis, and next‐generation sequencing was used to identify the exact species type of Nocardia in the bronchoalveolar lavage fluid (BALF) of the patient. RESULTS: Imaging and laboratory parameters preliminarily implied that the patient was infected with Nocardia with Sjogren's syndrome (SS), and NGS showed that the strain was N. terpenica. CONCLUSIONS: Accurate etiological diagnosis and corresponding antibiotics are key to improve the prognosis of pulmonary nocardiosis in this case. Nocardia pneumonia is rare in clinical practice; it is of great medical significance to improve the understanding of pulmonary nocardiosis.
format Online
Article
Text
id pubmed-8418472
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-84184722021-09-08 A rare case of pulmonary nocardiosis comorbid with Sjogren’s syndrome Peng, Yumeng Dong, Xiaoyan Zhu, Yongze Lv, Huoyang Ge, Yumei J Clin Lab Anal Case Report BACKGROUND: Nocardia is an opportunistic pathogen, which occurs in patients with autoimmune diseases and immune dysfunction, and can cause bacteremia and other life‐threatening complications. The clinical manifestations of Nocardia pneumonia are similar to tuberculous and other clinical common bacterial pneumonia, but its antibacterial treatments are different and detection methods are unique, which may lead patients to suffer for many years due to clinical misdiagnosis and missed diagnosis. METHODS: Imaging and laboratory examinations were performed for preliminary diagnosis, and next‐generation sequencing was used to identify the exact species type of Nocardia in the bronchoalveolar lavage fluid (BALF) of the patient. RESULTS: Imaging and laboratory parameters preliminarily implied that the patient was infected with Nocardia with Sjogren's syndrome (SS), and NGS showed that the strain was N. terpenica. CONCLUSIONS: Accurate etiological diagnosis and corresponding antibiotics are key to improve the prognosis of pulmonary nocardiosis in this case. Nocardia pneumonia is rare in clinical practice; it is of great medical significance to improve the understanding of pulmonary nocardiosis. John Wiley and Sons Inc. 2021-08-21 /pmc/articles/PMC8418472/ /pubmed/34418167 http://dx.doi.org/10.1002/jcla.23902 Text en © 2021 The Authors. Journal of Clinical Laboratory Analysis published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Peng, Yumeng
Dong, Xiaoyan
Zhu, Yongze
Lv, Huoyang
Ge, Yumei
A rare case of pulmonary nocardiosis comorbid with Sjogren’s syndrome
title A rare case of pulmonary nocardiosis comorbid with Sjogren’s syndrome
title_full A rare case of pulmonary nocardiosis comorbid with Sjogren’s syndrome
title_fullStr A rare case of pulmonary nocardiosis comorbid with Sjogren’s syndrome
title_full_unstemmed A rare case of pulmonary nocardiosis comorbid with Sjogren’s syndrome
title_short A rare case of pulmonary nocardiosis comorbid with Sjogren’s syndrome
title_sort rare case of pulmonary nocardiosis comorbid with sjogren’s syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418472/
https://www.ncbi.nlm.nih.gov/pubmed/34418167
http://dx.doi.org/10.1002/jcla.23902
work_keys_str_mv AT pengyumeng ararecaseofpulmonarynocardiosiscomorbidwithsjogrenssyndrome
AT dongxiaoyan ararecaseofpulmonarynocardiosiscomorbidwithsjogrenssyndrome
AT zhuyongze ararecaseofpulmonarynocardiosiscomorbidwithsjogrenssyndrome
AT lvhuoyang ararecaseofpulmonarynocardiosiscomorbidwithsjogrenssyndrome
AT geyumei ararecaseofpulmonarynocardiosiscomorbidwithsjogrenssyndrome
AT pengyumeng rarecaseofpulmonarynocardiosiscomorbidwithsjogrenssyndrome
AT dongxiaoyan rarecaseofpulmonarynocardiosiscomorbidwithsjogrenssyndrome
AT zhuyongze rarecaseofpulmonarynocardiosiscomorbidwithsjogrenssyndrome
AT lvhuoyang rarecaseofpulmonarynocardiosiscomorbidwithsjogrenssyndrome
AT geyumei rarecaseofpulmonarynocardiosiscomorbidwithsjogrenssyndrome