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A Case of New Onset Diabetes and Severe Diabetes Ketoacidosis in a Patient With COVID-19

Diabetic ketoacidosis (DKA) is a significant complication of poorly controlled diabetes. In diabetics, it typically occurs due to insulin deficiency resulting in lipolysis and subsequent ketone body formation and acidosis. The emergence of the COVID-19 infection has been associated with several comp...

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Autores principales: Patel, Latika, Ayad, Sarah, Rayad, Mohammad Nabil, Gergis, Kirolos, Ejikeme, Chidinma, Talpur, Afrah, Abdelazeem, Basel, Eckman, Ari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418556/
https://www.ncbi.nlm.nih.gov/pubmed/34513494
http://dx.doi.org/10.7759/cureus.16923
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author Patel, Latika
Ayad, Sarah
Rayad, Mohammad Nabil
Gergis, Kirolos
Ejikeme, Chidinma
Talpur, Afrah
Abdelazeem, Basel
Eckman, Ari
author_facet Patel, Latika
Ayad, Sarah
Rayad, Mohammad Nabil
Gergis, Kirolos
Ejikeme, Chidinma
Talpur, Afrah
Abdelazeem, Basel
Eckman, Ari
author_sort Patel, Latika
collection PubMed
description Diabetic ketoacidosis (DKA) is a significant complication of poorly controlled diabetes. In diabetics, it typically occurs due to insulin deficiency resulting in lipolysis and subsequent ketone body formation and acidosis. The emergence of the COVID-19 infection has been associated with several complications, with the most prominent being pulmonary and cardiovascular-related. However, in some cases, patients with COVID-19 infection present with diabetic ketoacidosis. The pathophysiology of DKA in COVID-19 infection is different and currently not completely understood. The manifestation of DKA in COVID-19 patients is associated with increased severity of mortality and length of stay in these patients. Here, we describe a patient with no past medical history who presented with COVID-19 symptoms and was found to be in DKA. This case report highlights the possible underlying pathophysiology associated with this complication.
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spelling pubmed-84185562021-09-10 A Case of New Onset Diabetes and Severe Diabetes Ketoacidosis in a Patient With COVID-19 Patel, Latika Ayad, Sarah Rayad, Mohammad Nabil Gergis, Kirolos Ejikeme, Chidinma Talpur, Afrah Abdelazeem, Basel Eckman, Ari Cureus Endocrinology/Diabetes/Metabolism Diabetic ketoacidosis (DKA) is a significant complication of poorly controlled diabetes. In diabetics, it typically occurs due to insulin deficiency resulting in lipolysis and subsequent ketone body formation and acidosis. The emergence of the COVID-19 infection has been associated with several complications, with the most prominent being pulmonary and cardiovascular-related. However, in some cases, patients with COVID-19 infection present with diabetic ketoacidosis. The pathophysiology of DKA in COVID-19 infection is different and currently not completely understood. The manifestation of DKA in COVID-19 patients is associated with increased severity of mortality and length of stay in these patients. Here, we describe a patient with no past medical history who presented with COVID-19 symptoms and was found to be in DKA. This case report highlights the possible underlying pathophysiology associated with this complication. Cureus 2021-08-05 /pmc/articles/PMC8418556/ /pubmed/34513494 http://dx.doi.org/10.7759/cureus.16923 Text en Copyright © 2021, Patel et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Patel, Latika
Ayad, Sarah
Rayad, Mohammad Nabil
Gergis, Kirolos
Ejikeme, Chidinma
Talpur, Afrah
Abdelazeem, Basel
Eckman, Ari
A Case of New Onset Diabetes and Severe Diabetes Ketoacidosis in a Patient With COVID-19
title A Case of New Onset Diabetes and Severe Diabetes Ketoacidosis in a Patient With COVID-19
title_full A Case of New Onset Diabetes and Severe Diabetes Ketoacidosis in a Patient With COVID-19
title_fullStr A Case of New Onset Diabetes and Severe Diabetes Ketoacidosis in a Patient With COVID-19
title_full_unstemmed A Case of New Onset Diabetes and Severe Diabetes Ketoacidosis in a Patient With COVID-19
title_short A Case of New Onset Diabetes and Severe Diabetes Ketoacidosis in a Patient With COVID-19
title_sort case of new onset diabetes and severe diabetes ketoacidosis in a patient with covid-19
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418556/
https://www.ncbi.nlm.nih.gov/pubmed/34513494
http://dx.doi.org/10.7759/cureus.16923
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