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Tail-vein injection of MSC-derived small extracellular vesicles facilitates the restoration of hippocampal neuronal morphology and function in APP / PS1 mice

Mesenchymal stem-cell-derived small extracellular vesicles (MSC-EVs), as a therapeutic agent, have shown great promise in the treatment of neurological diseases. To date, the neurorestorative effects and underlying mechanism of MSC-EVs in Alzheimer’s disease (AD) are not well known. Herein, we aimed...

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Detalles Bibliográficos
Autores principales: Wang, Han, Liu, Yuqi, Li, Junchen, Wang, Tian, Hei, Yue, Li, Huiming, Wang, Xue, Wang, Lina, Zhao, Ruijing, Liu, Weiping, Long, Qianfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418600/
https://www.ncbi.nlm.nih.gov/pubmed/34482379
http://dx.doi.org/10.1038/s41420-021-00620-y