The metabolic flexibility of quiescent CSC: implications for chemotherapy resistance

Quiescence has been observed in stem cells (SCs), including adult SCs and cancer SCs (CSCs). Conventional chemotherapies mostly target proliferating cancer cells, while the quiescent state favors CSCs escape to chemotherapeutic drugs, leaving risks for tumor recurrence or metastasis. The tumor micro...

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Detalles Bibliográficos
Autores principales: Chen, Kangchen, Zhang, Chenzhi, Ling, Sunbin, Wei, Rongli, Wang, Jianguo, Xu, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418609/
https://www.ncbi.nlm.nih.gov/pubmed/34482364
http://dx.doi.org/10.1038/s41419-021-04116-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418609/
https://www.ncbi.nlm.nih.gov/pubmed/34482364
http://dx.doi.org/10.1038/s41419-021-04116-6

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