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The metabolic flexibility of quiescent CSC: implications for chemotherapy resistance
Quiescence has been observed in stem cells (SCs), including adult SCs and cancer SCs (CSCs). Conventional chemotherapies mostly target proliferating cancer cells, while the quiescent state favors CSCs escape to chemotherapeutic drugs, leaving risks for tumor recurrence or metastasis. The tumor micro...
Autores principales: | Chen, Kangchen, Zhang, Chenzhi, Ling, Sunbin, Wei, Rongli, Wang, Jianguo, Xu, Xiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418609/ https://www.ncbi.nlm.nih.gov/pubmed/34482364 http://dx.doi.org/10.1038/s41419-021-04116-6 |
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