Circadian rhythms in bipolar disorder patient-derived neurons predict lithium response: Preliminary studies

Bipolar disorder (BD) is a neuropsychiatric illness defined by recurrent episodes of mania/hypomania, depression and circadian rhythm abnormalities. Lithium is an effective drug for BD, but 30–40% of patients fail to respond adequately to treatment. Previous work has demonstrated that lithium affect...

Descripción completa

Detalles Bibliográficos
Autores principales: Mishra, Himanshu K., Ying, Noelle M., Luis, Angelica, Wei, Heather, Nguyen, Metta, Nakhla, Timothy, Vandenburgh, Sara, Alda, Martin, Berrettini, Wade H., Brennand, Kristen J., Calabrese, Joseph R., Coryell, William H., Frye, Mark A., Gage, Fred H., Gershon, Elliot S., McInnis, Melvin G., Nievergelt, Caroline M., Nurnberger, John I., Shilling, Paul D., Oedegaard, Ketil J., Zandi, Peter P., Kelsoe, John R., Welsh, David K., McCarthy, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418615/
https://www.ncbi.nlm.nih.gov/pubmed/33674753
http://dx.doi.org/10.1038/s41380-021-01048-7

Ejemplares similares

Ejemplares similares