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Determining the Frequency of Cystic Echinococcosis among Suspected Cases Referred to Health Centers Southwest Iran, and Post-Treatment Serologic Follow-up

BACKGROUND: This study was designed to determine the frequency of hydatidosis in Khuzestan Province, Iran and to evaluate the antibody changes in infected individuals after treatment. METHODS: Overall, 454 sera were collected from health centers of Khuzestan Province, southern Iran (from 2013 to 201...

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Autores principales: Rafiei, Abdullah, Biranvand, Elahe, Nazari, Iraj, Bahraini, Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418658/
https://www.ncbi.nlm.nih.gov/pubmed/34557247
http://dx.doi.org/10.18502/ijpa.v16i2.6311
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author Rafiei, Abdullah
Biranvand, Elahe
Nazari, Iraj
Bahraini, Amin
author_facet Rafiei, Abdullah
Biranvand, Elahe
Nazari, Iraj
Bahraini, Amin
author_sort Rafiei, Abdullah
collection PubMed
description BACKGROUND: This study was designed to determine the frequency of hydatidosis in Khuzestan Province, Iran and to evaluate the antibody changes in infected individuals after treatment. METHODS: Overall, 454 sera were collected from health centers of Khuzestan Province, southern Iran (from 2013 to 2018). Demographic data such as age, gender and history of disease were recorded. Serum samples were investigated for antibody against CE by ELISA using antigen B. Thirty six of cases were followed up after treatment. RESULTS: Among the 454 evaluated cases, antibody against CE was detected in 184 (40.52%) including 115 (62.5%) females and 69 (37.5%) males. Age distribution was from 8–97 yr, the highest prevalence of hydatid cyst was observed in age group 40–49 years. Liver was the most infected organ (76.63%). Relapse of CE occurred in 23 of patients. In the majority of patients the antibody decreased, whereas in some cases increased CE antibody observed during post-treatment follow up. CONCLUSION: Current study indicated the high prevalence of hydatidosis and rate of relapse after treatment among suspected patients. Therefore, long periods and regular follow-up of patients after treatment is necessary and for these monitoring, antibody assay can be an appropriate method.
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spelling pubmed-84186582021-09-22 Determining the Frequency of Cystic Echinococcosis among Suspected Cases Referred to Health Centers Southwest Iran, and Post-Treatment Serologic Follow-up Rafiei, Abdullah Biranvand, Elahe Nazari, Iraj Bahraini, Amin Iran J Parasitol Short Communication BACKGROUND: This study was designed to determine the frequency of hydatidosis in Khuzestan Province, Iran and to evaluate the antibody changes in infected individuals after treatment. METHODS: Overall, 454 sera were collected from health centers of Khuzestan Province, southern Iran (from 2013 to 2018). Demographic data such as age, gender and history of disease were recorded. Serum samples were investigated for antibody against CE by ELISA using antigen B. Thirty six of cases were followed up after treatment. RESULTS: Among the 454 evaluated cases, antibody against CE was detected in 184 (40.52%) including 115 (62.5%) females and 69 (37.5%) males. Age distribution was from 8–97 yr, the highest prevalence of hydatid cyst was observed in age group 40–49 years. Liver was the most infected organ (76.63%). Relapse of CE occurred in 23 of patients. In the majority of patients the antibody decreased, whereas in some cases increased CE antibody observed during post-treatment follow up. CONCLUSION: Current study indicated the high prevalence of hydatidosis and rate of relapse after treatment among suspected patients. Therefore, long periods and regular follow-up of patients after treatment is necessary and for these monitoring, antibody assay can be an appropriate method. Tehran University of Medical Sciences 2021 /pmc/articles/PMC8418658/ /pubmed/34557247 http://dx.doi.org/10.18502/ijpa.v16i2.6311 Text en Copyright © 2021 Rafiei et al. Published by Tehran University of Medical Sciences https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International license (https://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.
spellingShingle Short Communication
Rafiei, Abdullah
Biranvand, Elahe
Nazari, Iraj
Bahraini, Amin
Determining the Frequency of Cystic Echinococcosis among Suspected Cases Referred to Health Centers Southwest Iran, and Post-Treatment Serologic Follow-up
title Determining the Frequency of Cystic Echinococcosis among Suspected Cases Referred to Health Centers Southwest Iran, and Post-Treatment Serologic Follow-up
title_full Determining the Frequency of Cystic Echinococcosis among Suspected Cases Referred to Health Centers Southwest Iran, and Post-Treatment Serologic Follow-up
title_fullStr Determining the Frequency of Cystic Echinococcosis among Suspected Cases Referred to Health Centers Southwest Iran, and Post-Treatment Serologic Follow-up
title_full_unstemmed Determining the Frequency of Cystic Echinococcosis among Suspected Cases Referred to Health Centers Southwest Iran, and Post-Treatment Serologic Follow-up
title_short Determining the Frequency of Cystic Echinococcosis among Suspected Cases Referred to Health Centers Southwest Iran, and Post-Treatment Serologic Follow-up
title_sort determining the frequency of cystic echinococcosis among suspected cases referred to health centers southwest iran, and post-treatment serologic follow-up
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418658/
https://www.ncbi.nlm.nih.gov/pubmed/34557247
http://dx.doi.org/10.18502/ijpa.v16i2.6311
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