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Extinction blunts paraventricular thalamic contributions to heroin relapse

Here, we use optogenetics and chemogenetics to investigate the contribution of the paraventricular thalamus (PVT) to nucleus accumbens (NAc) pathway in aversion and heroin relapse in two different heroin self-administration models in rats. In one model, rats undergo forced abstinence in the home cag...

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Detalles Bibliográficos
Autores principales: Giannotti, Giuseppe, Gong, Sheng, Fayette, Nicholas, Heinsbroek, Jasper A., Orfila, James E., Herson, Paco S., Ford, Christopher P., Peters, Jamie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418780/
https://www.ncbi.nlm.nih.gov/pubmed/34433067
http://dx.doi.org/10.1016/j.celrep.2021.109605

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