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Mineralocorticoid Receptor Antagonism in Chronic Kidney Disease

The overactivation of the mineralocorticoid receptor (MR) in animal models of chronic kidney disease (CKD) increases sodium retention and hypertension and provokes inflammation and fibrosis in the kidneys, blood vessels, and the heart; these processes play an important role in the progression of car...

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Detalles Bibliográficos
Autores principales: Georgianos, Panagiotis I., Agarwal, Rajiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418944/
https://www.ncbi.nlm.nih.gov/pubmed/34514191
http://dx.doi.org/10.1016/j.ekir.2021.05.027