PRMT5 disruption drives antitumor immunity in cervical cancer by reprogramming T cell-mediated response and regulating PD-L1 expression

Rationale: Protein arginine methyltransferase 5 (PRMT5) is an oncogene that promotes tumor cell proliferation, invasion and metastasis. However, the underlying mechanisms by which PRMT5 contributes to the progression of cervical cancer and especially the tumor microenvironment remain poorly understo...

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Detalles Bibliográficos
Autores principales: Jiang, Yongshuai, Yuan, Yuanyang, Chen, Ming, Li, Shengzhe, Bai, Jun, Zhang, Yuanteng, Sun, Ying, Wang, Guojue, Xu, Haiyan, Wang, Ziyu, Zheng, Yingxia, Nie, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419032/
https://www.ncbi.nlm.nih.gov/pubmed/34522232
http://dx.doi.org/10.7150/thno.59605

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