Co-delivery of autophagy inhibitor and gemcitabine using a pH-activatable core-shell nanobomb inhibits pancreatic cancer progression and metastasis

Background: Metastasis is one of the main reasons for the high mortality associated with pancreatic ductal adenocarcinoma (PDAC), and autophagy regulates the metastatic migration of tumor cells, their invasion of tissues, and their formation of focal adhesions. Inhibiting autophagy may suppress tumo...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoxiao, Tao, Yuan, He, Manmin, Deng, Miao, Guo, Rong, Sheng, Qinglin, Wang, Xuhui, Ren, Kebai, Li, Ting, He, Xuan, Zang, Shuya, Zhang, Zhirong, Li, Man, He, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419034/
https://www.ncbi.nlm.nih.gov/pubmed/34522207
http://dx.doi.org/10.7150/thno.60437

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