CD4+ T cell-mimicking nanoparticles encapsulating DIABLO/SMAC mimetics broadly neutralize HIV-1 and selectively kill HIV-1-infected cells

HIV-1 is a major global health challenge. The development of an effective vaccine and a therapeutic cure are top priorities. The creation of vaccines that focus an antibody response toward a particular epitope of a protein has shown promise, but the genetic diversity of HIV-1 stymies this progress....

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Detalles Bibliográficos
Autores principales: Campbell, Grant R., Zhuang, Jia, Zhang, Gang, Landa, Igor, Kubiatowicz, Luke J., Dehaini, Diana, Fang, Ronnie H., Zhang, Liangfang, Spector, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419049/
https://www.ncbi.nlm.nih.gov/pubmed/34522224
http://dx.doi.org/10.7150/thno.59728

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