Activating AhR alleviates cognitive deficits of Alzheimer's disease model mice by upregulating endogenous Aβ catabolic enzyme Neprilysin

Rationale: Neprilysin (NEP) is a major endogenous catabolic enzyme of amyloid β (Aβ). Previous studies have suggested that increasing NEP expression in animal models of Alzheimer's disease had an ameliorative effect. However, the underlying signaling pathway that regulates NEP expression remain...

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Detalles Bibliográficos
Autores principales: Qian, Cheng, Yang, Chunjie, Lu, Mengting, Bao, Jiaxin, Shen, Haiyan, Deng, Bingquan, Li, Shensen, Li, Wenwen, Zhang, Mu, Cao, Changchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419060/
https://www.ncbi.nlm.nih.gov/pubmed/34522212
http://dx.doi.org/10.7150/thno.61601

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