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Effective tools for RNA-derived therapeutics: siRNA interference or miRNA mimicry

The approval of the first small interfering RNA (siRNA) drug Patisiran by FDA in 2018 marks a new era of RNA interference (RNAi) therapeutics. MicroRNAs (miRNA), an important post-transcriptional gene regulator, are also the subject of both basic research and clinical trials. Both siRNA and miRNA mi...

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Detalles Bibliográficos
Autores principales: Wang, Peipei, Zhou, Yue, Richards, Arthur M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419061/
https://www.ncbi.nlm.nih.gov/pubmed/34522211
http://dx.doi.org/10.7150/thno.62642

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