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Metformin alleviates oxidative stress‐induced senescence of human lens epithelial cells via AMPK activation and autophagic flux restoration

Cataracts are the leading cause of blindness worldwide owing to the increasing proportion of elderly individuals in the population. The purpose of this study was to investigate whether metformin could alleviate the occurrence and development of age‐related cataract (ARC) and the underlying mechanism...

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Detalles Bibliográficos
Autores principales: Chen, Mengmeng, Zhang, Chunmei, Zhou, Nan, Wang, Xu, Su, Dongmei, Qi, Yanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419182/
https://www.ncbi.nlm.nih.gov/pubmed/34296521
http://dx.doi.org/10.1111/jcmm.16797