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Exogenous H(2)S prevents the nuclear translocation of PDC‐E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state

Hydrogen sulphide (H(2)S) inhibits vascular smooth muscle cell (VSMC) proliferation induced by hyperglycaemia and hyperlipidaemia; however, the mechanisms are unclear. Here, we observed lower H(2)S levels and higher expression of the proliferation‐related proteins PCNA and cyclin D1 in db/db mouse a...

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Detalles Bibliográficos
Autores principales: Zhang, Linxue, Jiang, Xiaoshu, Liu, Ning, Li, Mingyu, Kang, Jiaxin, Chen, Lingxue, Tang, Jingyuan, Dong, Shiyun, Lu, Fanghao, Zhang, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419187/
https://www.ncbi.nlm.nih.gov/pubmed/34418283
http://dx.doi.org/10.1111/jcmm.16688