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Lamivudine improves cognitive decline in SAMP8 mice: Integrating in vivo pharmacological evaluation and network pharmacology

The reverse transcriptase inhibitors such as lamivudine (3TC) play important roles in anti‐ageing, but their effects on neurodegenerative diseases caused by ageing are not clear, especially on the functions of the nervous system such as cognition. In this study, we administered 3TC to senescence‐acc...

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Detalles Bibliográficos
Autores principales: Li, Ming, Zhao, Jie, Tang, Qi, Zhang, Qingchen, Wang, Yong, Zhang, Jian, Hao, Yingying, Bai, Xiaohui, Lu, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419189/
https://www.ncbi.nlm.nih.gov/pubmed/34374199
http://dx.doi.org/10.1111/jcmm.16811