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Detection of Urinary Exosomal HSD11B2 mRNA Expression: A Useful Novel Tool for the Diagnostic Approach of Dysfunctional 11β-HSD2-Related Hypertension

OBJECTIVE: Apparent mineralocorticoid excess (AME) is an autosomal recessive disorder caused by the 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2) enzyme deficiency, traditionally assessed by measuring either the urinary cortisol metabolites ratio (tetrahydrocortisol+allotetrahydrocortisol/tetra...

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Detalles Bibliográficos
Autores principales:	De Santis, Domenica, Castagna, Annalisa, Danese, Elisa, Udali, Silvia, Martinelli, Nicola, Morandini, Francesca, Veneri, Mariangela, Bertolone, Lorenzo, Olivieri, Oliviero, Friso, Simonetta, Pizzolo, Francesca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419411/ https://www.ncbi.nlm.nih.gov/pubmed/34497581 http://dx.doi.org/10.3389/fendo.2021.681974

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