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Glucotoxicity Activation of IL6 and IL11 and Subsequent Induction of Fibrosis May Be Involved in the Pathogenesis of Islet Dysfunction

Background: Islet dysfunction is the main pathological process of type 2 diabetes mellitus (T2DM). Fibrosis causes islet dysfunction, but the current mechanism is still unclear. Here, bioinformatics analysis identified gene clusters closely related to T2DM and differentially expressed genes related...

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Detalles Bibliográficos
Autores principales:	Lu, Liqin, Zhuang, Lili, Shen, Ximei, Yang, Liyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419433/ https://www.ncbi.nlm.nih.gov/pubmed/34497830 http://dx.doi.org/10.3389/fmolb.2021.708127

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