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Transmission Dynamics of Corynebacterium spp. Within Two Danish Dairy Cattle Herds

Intramammary infections (IMI) can cause mastitis, a prevalent and costly infectious disease in dairy cattle worldwide. The IMI is caused by a range of bacteria, including Corynebacterium spp. Knowledge of the transmission dynamics of pathogens is generally sparse but essential to support decision-ma...

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Autores principales: Kirkeby, Carsten, Halasa, Tariq, Farre, Michael, Chehabi, Galal Nazih, Græsbøll, Kaare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419450/
https://www.ncbi.nlm.nih.gov/pubmed/34497843
http://dx.doi.org/10.3389/fvets.2021.735345
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author Kirkeby, Carsten
Halasa, Tariq
Farre, Michael
Chehabi, Galal Nazih
Græsbøll, Kaare
author_facet Kirkeby, Carsten
Halasa, Tariq
Farre, Michael
Chehabi, Galal Nazih
Græsbøll, Kaare
author_sort Kirkeby, Carsten
collection PubMed
description Intramammary infections (IMI) can cause mastitis, a prevalent and costly infectious disease in dairy cattle worldwide. The IMI is caused by a range of bacteria, including Corynebacterium spp. Knowledge of the transmission dynamics of pathogens is generally sparse but essential to support decision-making; such as input to bioeconomic models. In this observational study, we explored the transmission dynamics of Corynebacterium spp. in two different Danish dairy cattle herds by testing monthly quarter-level milk samples of all lactating cows for 1 year. We estimated the prevalence for herd 1 and 2 to 24 and 11.7%, respectively, and the mean quarter-level incidence to be 8 and 6.5% per month, respectively. We compared a model for indirect transmission via the environment with a model with the direct contagious transmission and found that the latter model best explained the data. We estimated the daily mean quarter-level transmission rate to be 0.016 and 0.018 cases/quarter-day for herd 1 and 2, respectively. The mean recovery rate was 0.012 and 0.016 for herd 1 and 2, respectively. Consequently, the basic reproduction number for herd 1 and 2 was 1.27 and 1.10, respectively. This study highlights that Corynebacterium spp. can be prevalent within a herd and transmit directly between cows. Thus, future studies should investigate cost-effective control measures against Corynebacterium spp.
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spelling pubmed-84194502021-09-07 Transmission Dynamics of Corynebacterium spp. Within Two Danish Dairy Cattle Herds Kirkeby, Carsten Halasa, Tariq Farre, Michael Chehabi, Galal Nazih Græsbøll, Kaare Front Vet Sci Veterinary Science Intramammary infections (IMI) can cause mastitis, a prevalent and costly infectious disease in dairy cattle worldwide. The IMI is caused by a range of bacteria, including Corynebacterium spp. Knowledge of the transmission dynamics of pathogens is generally sparse but essential to support decision-making; such as input to bioeconomic models. In this observational study, we explored the transmission dynamics of Corynebacterium spp. in two different Danish dairy cattle herds by testing monthly quarter-level milk samples of all lactating cows for 1 year. We estimated the prevalence for herd 1 and 2 to 24 and 11.7%, respectively, and the mean quarter-level incidence to be 8 and 6.5% per month, respectively. We compared a model for indirect transmission via the environment with a model with the direct contagious transmission and found that the latter model best explained the data. We estimated the daily mean quarter-level transmission rate to be 0.016 and 0.018 cases/quarter-day for herd 1 and 2, respectively. The mean recovery rate was 0.012 and 0.016 for herd 1 and 2, respectively. Consequently, the basic reproduction number for herd 1 and 2 was 1.27 and 1.10, respectively. This study highlights that Corynebacterium spp. can be prevalent within a herd and transmit directly between cows. Thus, future studies should investigate cost-effective control measures against Corynebacterium spp. Frontiers Media S.A. 2021-08-23 /pmc/articles/PMC8419450/ /pubmed/34497843 http://dx.doi.org/10.3389/fvets.2021.735345 Text en Copyright © 2021 Kirkeby, Halasa, Farre, Chehabi and Græsbøll. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Kirkeby, Carsten
Halasa, Tariq
Farre, Michael
Chehabi, Galal Nazih
Græsbøll, Kaare
Transmission Dynamics of Corynebacterium spp. Within Two Danish Dairy Cattle Herds
title Transmission Dynamics of Corynebacterium spp. Within Two Danish Dairy Cattle Herds
title_full Transmission Dynamics of Corynebacterium spp. Within Two Danish Dairy Cattle Herds
title_fullStr Transmission Dynamics of Corynebacterium spp. Within Two Danish Dairy Cattle Herds
title_full_unstemmed Transmission Dynamics of Corynebacterium spp. Within Two Danish Dairy Cattle Herds
title_short Transmission Dynamics of Corynebacterium spp. Within Two Danish Dairy Cattle Herds
title_sort transmission dynamics of corynebacterium spp. within two danish dairy cattle herds
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419450/
https://www.ncbi.nlm.nih.gov/pubmed/34497843
http://dx.doi.org/10.3389/fvets.2021.735345
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