Access to 2,6-Dipropargylated BODIPYs as “Clickable” Congeners of Pyrromethene-567 Dye: Photostability and Synthetic Versatility

[Image: see text] Hitherto unreported 2,6-dipropargyl-1,3,5,7-tetramethyl BODIPYs can be efficiently prepared by a Nicholas reaction/decomplexation protocol from 1,3,5,7-tetramethyl BODIPYs. The title compounds, which improve the BODIPY photostability by retaining their inherent photophysical and ph...

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Detalles Bibliográficos
Autores principales: Uriel, Clara, Gómez, Ana M., García Martínez de la Hidalga, Enrique, Bañuelos, Jorge, Garcia-Moreno, Inmaculada, López, J. Cristobal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419863/
https://www.ncbi.nlm.nih.gov/pubmed/34403255
http://dx.doi.org/10.1021/acs.orglett.1c02380
Descripción
Sumario:[Image: see text] Hitherto unreported 2,6-dipropargyl-1,3,5,7-tetramethyl BODIPYs can be efficiently prepared by a Nicholas reaction/decomplexation protocol from 1,3,5,7-tetramethyl BODIPYs. The title compounds, which improve the BODIPY photostability by retaining their inherent photophysical and photochemical properties, can be engaged in efficient copper(I)-catalyzed azide–alkyne cycloaddition (CuAAC) “click-type” reactions with azido derivatives to provide all-BODIPY-triads or conjugated BODIPYs.

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