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The Human and Mouse Islet Peptidome: Effects of Obesity and Type 2 Diabetes, and Assessment of Intraislet Production of Glucagon-like Peptide-1

[Image: see text] To characterize the impact of metabolic disease on the peptidome of human and mouse pancreatic islets, LC-MS was used to analyze extracts of human and mouse islets, purified mouse alpha, beta, and delta cells, supernatants from mouse islet incubations, and plasma from patients with...

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Detalles Bibliográficos
Autores principales:	Galvin, Sam G., Kay, Richard G., Foreman, Rachel, Larraufie, Pierre, Meek, Claire L., Biggs, Emma, Ravn, Peter, Jermutus, Lutz, Reimann, Frank, Gribble, Fiona M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419866/ https://www.ncbi.nlm.nih.gov/pubmed/34423991 http://dx.doi.org/10.1021/acs.jproteome.1c00463

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