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Innate immune responses after stimulation with Toll-like receptor agonists in ex vivo microglial cultures and an in vivo model using mice with reduced microglia

BACKGROUND: Past experiments studying innate immunity in the central nervous system (CNS) utilized microglia obtained from neonatal mouse brain, which differ developmentally from adult microglia. These differences might impact our current understanding of the role of microglia in CNS development, fu...

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Detalles Bibliográficos
Autores principales:	Carroll, James A., Race, Brent, Williams, Katie, Striebel, James F., Chesebro, Bruce
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419892/ https://www.ncbi.nlm.nih.gov/pubmed/34488805 http://dx.doi.org/10.1186/s12974-021-02240-w

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