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Injectable exosome-functionalized extracellular matrix hydrogel for metabolism balance and pyroptosis regulation in intervertebral disc degeneration
Exosome therapy is a promising therapeutic approach for intervertebral disc degeneration (IVDD) and achieves its therapeutic effects by regulating metabolic disorders, the microenvironment and cell homeostasis with the sustained release of microRNAs, proteins, and transcription factors. However, the...
Autores principales: | Xing, Hongyuan, Zhang, Zengjie, Mao, Qijiang, Wang, Chenggui, Zhou, Youlong, Zhou, Xiaopeng, Ying, Liwei, Xu, Haibin, Hu, Shaojun, Zhang, Ning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419940/ https://www.ncbi.nlm.nih.gov/pubmed/34488795 http://dx.doi.org/10.1186/s12951-021-00991-5 |
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