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Injectable exosome-functionalized extracellular matrix hydrogel for metabolism balance and pyroptosis regulation in intervertebral disc degeneration

Exosome therapy is a promising therapeutic approach for intervertebral disc degeneration (IVDD) and achieves its therapeutic effects by regulating metabolic disorders, the microenvironment and cell homeostasis with the sustained release of microRNAs, proteins, and transcription factors. However, the...

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Detalles Bibliográficos
Autores principales: Xing, Hongyuan, Zhang, Zengjie, Mao, Qijiang, Wang, Chenggui, Zhou, Youlong, Zhou, Xiaopeng, Ying, Liwei, Xu, Haibin, Hu, Shaojun, Zhang, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419940/
https://www.ncbi.nlm.nih.gov/pubmed/34488795
http://dx.doi.org/10.1186/s12951-021-00991-5

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