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The regulatory pattern of target gene expression by aberrant enhancer methylation in glioblastoma

BACKGROUND: Glioblastoma multiforme (GBM) is the most common and aggressive primary malignant brain tumor with grim prognosis. Aberrant DNA methylation is an epigenetic mechanism that promotes GBM carcinogenesis, while the function of DNA methylation at enhancer regions in GBM remains poorly describ...

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Detalles Bibliográficos
Autores principales:	Zhao, Xiaoxiao, Ji, Jianghuai, Wang, Shijia, Wang, Rendong, Yu, Qiuhong, Li, Dongguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420065/ https://www.ncbi.nlm.nih.gov/pubmed/34482818 http://dx.doi.org/10.1186/s12859-021-04345-8

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