Cargando…

Mathematical modeling of COVID-19 transmission dynamics between healthcare workers and community

Corona-virus disease 2019 (COVID-19) is an infectious disease that has affected different groups of humankind such as farmers, soldiers, drivers, educators, students, healthcare workers and many others. The transmission rate of the disease varies from one group to another depending on the contact ra...

Descripción completa

Detalles Bibliográficos
Autores principales: Masandawa, Lemjini, Mirau, Silas Steven, Mbalawata, Isambi Sailon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420379/
https://www.ncbi.nlm.nih.gov/pubmed/34513578
http://dx.doi.org/10.1016/j.rinp.2021.104731
_version_ 1783748909475037184
author Masandawa, Lemjini
Mirau, Silas Steven
Mbalawata, Isambi Sailon
author_facet Masandawa, Lemjini
Mirau, Silas Steven
Mbalawata, Isambi Sailon
author_sort Masandawa, Lemjini
collection PubMed
description Corona-virus disease 2019 (COVID-19) is an infectious disease that has affected different groups of humankind such as farmers, soldiers, drivers, educators, students, healthcare workers and many others. The transmission rate of the disease varies from one group to another depending on the contact rate. Healthcare workers are at a high risk of contracting the disease due to the high contact rate with patients. So far, there exists no mathematical model which combines both public control measures (as a parameter) and healthcare workers (as an independent compartment). Combining these two in a given mathematical model is very important because healthcare workers are protected through effective use of personal protective equipment, and control measures help to minimize the spread of COVID-19 in the community. This paper presents a mathematical model named SWE [Formula: see text] HR; susceptible individuals (S), healthcare workers (W), exposed (E), symptomatic infectious ([Formula: see text]), asymptomatic infectious ([Formula: see text]), hospitalized (H), recovered (R). The value of basic reproduction number [Formula: see text] for all parameters in this study is 2.8540. In the absence of personal protective equipment [Formula: see text] and control measure in the public [Formula: see text] , the value of [Formula: see text] which implies the presence of the disease. When [Formula: see text] and [Formula: see text] were introduced in the model, basic reproduction number is reduced to 0.4606, indicating the absence of disease in the community. Numerical solutions are simulated by using Runge–Kutta fourth-order method. Sensitivity analysis is performed to presents the most significant parameter. Furthermore, identifiability of model parameters is done using the least square method. The results indicated that protection of healthcare workers can be achieved through effective use of personal protective equipment by healthcare workers and minimization of transmission of COVID-19 in the general public by the implementation of control measures. Generally, this paper emphasizes the importance of using protective measures.
format Online
Article
Text
id pubmed-8420379
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher The Authors. Published by Elsevier B.V.
record_format MEDLINE/PubMed
spelling pubmed-84203792021-09-07 Mathematical modeling of COVID-19 transmission dynamics between healthcare workers and community Masandawa, Lemjini Mirau, Silas Steven Mbalawata, Isambi Sailon Results Phys Article Corona-virus disease 2019 (COVID-19) is an infectious disease that has affected different groups of humankind such as farmers, soldiers, drivers, educators, students, healthcare workers and many others. The transmission rate of the disease varies from one group to another depending on the contact rate. Healthcare workers are at a high risk of contracting the disease due to the high contact rate with patients. So far, there exists no mathematical model which combines both public control measures (as a parameter) and healthcare workers (as an independent compartment). Combining these two in a given mathematical model is very important because healthcare workers are protected through effective use of personal protective equipment, and control measures help to minimize the spread of COVID-19 in the community. This paper presents a mathematical model named SWE [Formula: see text] HR; susceptible individuals (S), healthcare workers (W), exposed (E), symptomatic infectious ([Formula: see text]), asymptomatic infectious ([Formula: see text]), hospitalized (H), recovered (R). The value of basic reproduction number [Formula: see text] for all parameters in this study is 2.8540. In the absence of personal protective equipment [Formula: see text] and control measure in the public [Formula: see text] , the value of [Formula: see text] which implies the presence of the disease. When [Formula: see text] and [Formula: see text] were introduced in the model, basic reproduction number is reduced to 0.4606, indicating the absence of disease in the community. Numerical solutions are simulated by using Runge–Kutta fourth-order method. Sensitivity analysis is performed to presents the most significant parameter. Furthermore, identifiability of model parameters is done using the least square method. The results indicated that protection of healthcare workers can be achieved through effective use of personal protective equipment by healthcare workers and minimization of transmission of COVID-19 in the general public by the implementation of control measures. Generally, this paper emphasizes the importance of using protective measures. The Authors. Published by Elsevier B.V. 2021-10 2021-09-06 /pmc/articles/PMC8420379/ /pubmed/34513578 http://dx.doi.org/10.1016/j.rinp.2021.104731 Text en © 2021 The Authors. Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Masandawa, Lemjini
Mirau, Silas Steven
Mbalawata, Isambi Sailon
Mathematical modeling of COVID-19 transmission dynamics between healthcare workers and community
title Mathematical modeling of COVID-19 transmission dynamics between healthcare workers and community
title_full Mathematical modeling of COVID-19 transmission dynamics between healthcare workers and community
title_fullStr Mathematical modeling of COVID-19 transmission dynamics between healthcare workers and community
title_full_unstemmed Mathematical modeling of COVID-19 transmission dynamics between healthcare workers and community
title_short Mathematical modeling of COVID-19 transmission dynamics between healthcare workers and community
title_sort mathematical modeling of covid-19 transmission dynamics between healthcare workers and community
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420379/
https://www.ncbi.nlm.nih.gov/pubmed/34513578
http://dx.doi.org/10.1016/j.rinp.2021.104731
work_keys_str_mv AT masandawalemjini mathematicalmodelingofcovid19transmissiondynamicsbetweenhealthcareworkersandcommunity
AT mirausilassteven mathematicalmodelingofcovid19transmissiondynamicsbetweenhealthcareworkersandcommunity
AT mbalawataisambisailon mathematicalmodelingofcovid19transmissiondynamicsbetweenhealthcareworkersandcommunity